Megestrol acetate 160 mg Tablets

Megestrol Acetate tablets come under the brand name SAVOSTROL-160. Megestrol Acetate tablets are a synthetic progestin primarily used to treat advanced breast or endometrial cancer by inhibiting hormone-dependent tumor growth. They are also prescribed off-label to stimulate appetite and promote weight gain in patients with cachexia, particularly those with AIDS or cancer-related wasting syndrome. The drug works by mimicking progesterone, altering hormone levels, and increasing appetite through central nervous system effects.

Megestrol Acetate tablets are manufactured by an ISO and GMP-certified pharmaceutical company, Sanify Healthcare. Sanify Healthcare manufactures and supplies the ultimate formulations of Megestrol Acetate tablets worldwide. Sanify Healthcare also offers great career opportunities for various young entrepreneurs who want to start their careers in the healthcare profession under support and guidance.

Benefits of Megestrol Acetate Tablets

Megestrol Acetate tablets have various medical advantages, given below:

• Stimulates appetite in cachexia (AIDS/cancer-related wasting).
• Promotes weight gain in malnourished patients.
• Used as palliative therapy in advanced breast cancer.
• Effective in managing metastatic endometrial cancer.
• Helps reduce nausea and improve nutritional intake.
• Oral administration ensures convenient dosing.
• It can improve the quality of life in wasting syndromes.
• It may reduce cancer-related fatigue in some patients.
• Alternative option when other hormonal therapies fail.
• Supports better tolerance of cancer treatments.

Dosage Instructions for Megestrol Acetate Tablets

The directions for using Megestrol Acetate tablets are mentioned below:

• Take the tablet as prescribed by your doctor.
• Swallow the tablet whole with water; do not crush or chew.
• It can be taken with or without food, but consistency is key.
• Do not exceed the recommended dosage.
• Continue use as directed, even if symptoms improve.

Storage Instructions for Megestrol Acetate Tablets

The storage rules for Megestrol Acetate tablets are given below:

• Keep it at room temperature.
• Keep it in a cool and dry place.
• Protect it from sunlight.
• Keep it away from the reach of children and pets.
• Do not keep it in moisture.
• Keep it away from freezing.

Precautions for Using Megestrol Acetate Tablets

The safety measures for using Megestrol Acetate tablets are:

• Avoid in pregnancy (risk of fetal harm).
• Monitor for signs of blood clots (thromboembolism risk).
• Use caution in patients with diabetes (may increase blood sugar).
• Watch for adrenal suppression with long-term use.
• Not recommended for patients with known hypersensitivity.
• Use cautiously in those with liver or kidney impairment.
• May cause fluid retention (caution in heart disease).
• Risk of deep vein thrombosis (DVT) with prolonged use.
• Monitor for mood changes or depression.
• Use the lowest effective dose for the shortest duration.
• Regular blood pressure checks are recommended.

Side Effects of Having Megestrol Acetate Tablets 

The side effects of consuming Megestrol Acetate tablets are given below:

• Weight gain
• Constipation
• Insomnia
• Weakness
• Diarrhea
• Nausea
• Vomiting
• Dryness in mouth
• Hepatomegaly
• Decreased white blood cell count
• Increased lactate level in the blood
• Paresthesia
• Urinary tract infection

Frequently Asked Questions (FAQs)

How do Megestrol Acetate tablets help cancer patients?

Blocks estrogen-driven tumor growth in hormone-sensitive cancers.

Can Megestrol Acetate be used for non-cancer weight gain?

Not recommended – high risk of clots/diabetes.

When does appetite improvement start?

Begins in 1-2 weeks, with maximum effect by 8 weeks.

How do Megestrol Acetate tablets affect men?

Crushes testosterone – causes impotence and breast growth.